Monday, October 26, 2009

H1N1 Flu: Key Flu Indicators

Each week CDC analyzes information about influenza disease activity in the United States and publishes findings of key flu indicators in a report called FluView. During the week of October 11-17, 2009, a review of the key indictors found that influenza activity continued to increase in the United States from the previous week. Below is a summary of the most recent key indicators:

- Visits to doctors for influenza-like illness (ILI) increased steeply since last week in the United States, and overall, are much higher than what is expected for this time of the year. ILI activity now is higher than what is seen during the peak of many regular flu seasons.

- Total influenza hospitalization rates for laboratory-confirmed flu are climbing and are higher than expected for this time of year.

- The proportion of deaths attributed to pneumonia and influenza (P&I) based on the 122 Cities Report has increased and has been higher than what is expected at this time of year for two weeks. In addition, 11 flu-related pediatric deaths were reported this week; 9 of these deaths were confirmed 2009 H1N1, and two were influenza A viruses, but were not subtyped. Since April 2009, CDC has received reports of 95 laboratory-confirmed pediatric 2009 H1N1 deaths and another 7 pediatric deaths that were laboratory confirmed as influenza, but where the flu virus subtype was not determined.

- Forty-six states are reporting widespread influenza activity at this time. They are: Alabama, Alaska, Arizona, Arkansas, California, Colorado, Delaware, Florida, Georgia, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin, and Wyoming. This many reports of widespread activity are unprecedented during seasonal flu.

- Almost all of the influenza viruses identified so far are 2009 H1N1 influenza A viruses. These viruses remain similar to the virus chosen for the 2009 H1N1 vaccine, and remain susceptible to the antiviral drugs oseltamivir and zanamivir with rare exception.

Friday, October 23, 2009

Can H1N1 flu virus in pregnancy change genes in the brains of the unborn?

Swine flu in pregnant women may change the genes of unborn children resulting in damage to the hippocampus. According to the article, neuroscientists found that the H1N1 changes the genes that control brain growth and development in the unborn child. The scientists published their report in the medical journal, European Neuropsychopharmacology, listing more than a dozen genes that the swine flu virus adversely affected.

Geneticists want to know how some of those genes are tied to the development of the hippocampus, a component of the brain involved in long term memory and spatial navigation.

If the flu itself damages the hippocampus, the result could be linked to autism, Alzheimer’s and schizophrenia. Let's take a logical look at the original study, published in the medical journal, European Neuropsychopharmacology.

The team of researchers and lead scientist, Hossein Fatemi as part of the experiement, injected pregnant female mice with the H1N1 and studied the brains of the newborn mice. Mice exposed to the H1N1 virus in the womb had a fifteen percent reduction in the size of their hippocampus. Scientists also found twelve other genes that the flu virus negatively affected.

The study has been done on mice, not people. But does the study confirm the public health recommendation that pregnant women need to be vaccinated against the H1N1 virus? If so, the question consumers need to ask is whether getting flu shots of the killed virus do anything to the brains of the infants yet unborn when the pregnant women get the recommended shots? On one hand, you don't want to get the flu when pregnant. Your immune system is compromised when you're pregnant. You want protection.

On the other hand, the question is how is your unborn baby's brain going to be affected by the dead virus, the mercury in the shot, or any other factor? You don't want the flu, and vaccination is a priority for pregnant women. But what will the hippocampus of your baby's brain look like? You're not going to be given the live virus up the nose because you'll be shedding it for days after vaccination to other family members, people standing next to you in the stores you shop at, and co-workers.
 
Swine Flu Virus.
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